(glutamate—ammonia-ligase) adenylyltransferase

The correct title of this article is [Glutamate—ammonia-ligase] adenylyltransferase. The substitution or omission of any < > [ ] { } is because of technical restrictions.

[glutamate—ammonia-ligase] adenylyltransferase
Identifiers
EC number	2.7.7.42
CAS number	Template:CAS
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a [glutamate—ammonia-ligase] adenylyltransferase (EC 2.7.7.42) is an enzyme that catalyzes the chemical reaction

ATP + [L-glutamate:ammonia ligase (ADP-forming)] $\rightleftharpoons$ diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]

Thus, the two substrates of this enzyme are ATP and L-glutamate:ammonia ligase (ADP-forming), whereas its two products are diphosphate and [[adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]]].

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:[L-glutamate:ammonia ligase (ADP-forming)] adenylyltransferase. Other names in common use include glutamine-synthetase adenylyltransferase, ATP:glutamine synthetase adenylyltransferase, and adenosine triphosphate:glutamine synthetase adenylyltransferase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V4A.