17-alpha-hydroxyprogesterone aldolase
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(Redirected from 17a-hydroxyprogesterone aldolase)
| 17-alpha-hydroxyprogesterone aldolase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.1.2.30 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a 17alpha-hydroxyprogesterone aldolase (EC 4.1.2.30) is an enzyme that catalyzes the chemical reaction
- 17alpha-hydroxyprogesterone
4-androstene-3,17-dione + acetaldehyde
Hence, this enzyme has one substrate, 17-alpha-hydroxyprogesterone, and two products, 4-androstene-3,17-dione and acetaldehyde.
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming). Other names in common use include C-17/C-20 lyase, and 17alpha-hydroxyprogesterone acetaldehyde-lyase. This enzyme participates in androgen and estrogen metabolism.
References
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