4-Methylethcathinone

Systematic (IUPAC) name
(RS)-2-ethylamino-1-(4-methylphenyl)propan-1-one
Clinical data
Legal status	DE: Anlage II (Prohibited) UK: Class B US: Schedule I Class C (NZ), I-P (Poland)
Identifiers
CAS Number	1225617-18-4 Y 1266688-86-1 (hydrochloride)
PubChem	CID: 52988258
ChemSpider	25630091
UNII	9665W17SH3 Y
Synonyms	4-methyl-N-ethylcathinone; 2-ethylamino-1-p-tolylpropan-1-one
Chemical data
Formula	C12H17NO
Molecular mass	191.27 g/mol
SMILES Cc1ccc(cc1)C(=O)C(C)NCC
InChI InChI=1S/C12H17NO/c1-4-13-10(3)12(14)11-7-5-9(2)6-8-11/h5-8,10,13H,4H2,1-3H3 N Key:ZOXZWYWOECCBSH-UHFFFAOYSA-N N
NY (what is this?)  (verify)

4-Methylethcathinone or 4-MEC is a chemical that bears a chemical resemblance to mephedrone. Due to its similarity to mephedrone, it is thought to be a stimulant and entactogen drug of the phenethylamine, amphetamine, and cathinone chemical classes. It has been marketed alone or in mixtures with other substituted cathinones under the name "NRG-2", although other blends such as "NRG-1" may have been more ambiguous with their ingredients.

4-MEC is reported to have been used as the active ingredient in fake "Ecstasy" pills in some countries such as New Zealand.

Psychopharmacology

4-MEC is a synthetic stimulant with empathogenic effects that is chemically similar to methcathinone. It became available online in 2010 and has been sold as replacement for 4-methylmethcathinone (mephedrone). It has an extremely short history of human use. As of 2011, it is most often found as a powder (either represented as 4-methylethcathinone or included in powder products that don't specify their active ingredients) and has appeared in some samples of "NRG-2", although it has also been found in tablet form.

Some reports of 4-methylethcathinone use involve redosing ("boosting" or "bumping") multiple times. Users sometimes mix oral and insufflated, taking some 4-methylethcathinone orally, then insufflating some, then taking more orally. Because of the common desire to recapture the pleasurable initial high, redoses are sometimes higher than the initial dose or are spaced closely together in time. Many users report having difficulty not redosing after using a strong dose if more 4-methylethcathinone is available when they are starting to come down. Experience reports in which users find themselves unexpectedly consuming a gram or more of 4-methylethcathinone are common.

Recreational use

Some users have injected the drug intravenously. This requires heating the water/4-MEC solution in order for 4-MEC to dissolve. Injecting 4-MEC appears to be rough on veins and is sometimes accompanied by a burning sensation; for this reason 4-MEC should be diluted as much as possible. Intravenous dosages are comparable to oral ones, although more care should be given to safety (with regard to possibility of overdose and long-term effects).

See also

• 4-Ethylmethcathinone
• 4-Methylbuphedrone
• 4-Methylcathinone
• 4-Methylpentedrone
• Substituted cathinone
• Benzedrone
• Mephedrone