A-84,543

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A-84,543
A-84543 structure.png
Systematic (IUPAC) name
3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine
Identifiers
CAS Number 161416-43-9 YesY
PubChem CID: 178052
ChemSpider 155000 YesY
ChEMBL CHEMBL127071 YesY
Chemical data
Formula C11H16N2O
Molecular mass 192.257
  • CN(CCC1)[C@@H]1COC2=CC=CN=C2
  • InChI=1S/C11H16N2O/c1-13-7-3-4-10(13)9-14-11-5-2-6-12-8-11/h2,5-6,8,10H,3-4,7,9H2,1H3/t10-/m0/s1 YesY
  • Key:MVLJPWPLDPHKST-JTQLQIEISA-N YesY
  (verify)

A-84543 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It is widely used in scientific research into the structure and function of this receptor subtype and has been the lead compound for the development of a large family of related derivatives.[1][2][2][3][4]

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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