A-86929

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A-86929
A-86929 structure.png
Names
IUPAC name
9,10-Dihydroxy-2-propyl-4,5,5a(R),6,7,11b(S)-hexahydrobenzo[f]thieno[2,3-c]quinoline
Identifiers
166591-11-3 N
ChEMBL ChEMBL28338 YesY
ChemSpider 8017113 YesY
Jmol 3D model Interactive image
PubChem 9841398
  • InChI=1S/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m1/s1 YesY
    Key: REHAKLRYABHSQJ-KDOFPFPSSA-N YesY
  • InChI=1/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m1/s1
    Key: REHAKLRYABHSQJ-KDOFPFPSBO
  • Oc1cc3c(cc1O)CCC4C3c2cc(CCC)sc2CN4
Properties
C18H21NO2S
Molar mass 315.429 g/mol
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

A-86929 is a synthetic compound that acts as a selective dopamine receptor D1 agonist.[1][2] It was developed as a possible treatment for Parkinson's disease,[3] as well as for other applications such as treatment of cocaine addiction,[4][5] but while it had reasonable efficacy in humans it also caused dyskinesias and has not been continued.[6][7] It has mainly been used as its diacetate ester prodrug adrogolide (ABT-431), which has better bioavailability.[8][9]

Adrogolide

References

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