AM-905

AM-905

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Systematic (IUPAC) name
(6aR,9R,10aR)-3-[(E)-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Identifiers
PubChem	CID: 9998522
ChemSpider	8174103 Y
ChEMBL	CHEMBL127848 Y
Chemical data
Formula	C23H34O3
Molecular mass	358.513 g/mol
SMILES CCCCCC=Cc(cc1O)cc(OC(C)(C)C2CC3)c1C2CC3CO
InChI InChI=1S/C23H34O3/c1-4-5-6-7-8-9-16-13-20(25)22-18-12-17(15-24)10-11-19(18)23(2,3)26-21(22)14-16/h8-9,13-14,17-19,24-25H,4-7,10-12,15H2,1-3H3/b9-8+/t17-,18-,19-/m1/s1 Y Key:NJIKRWBGUIYKJM-OKMMTOMJSA-N Y
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AM-905 is an analgesic drug which is a cannabinoid agonist with a conformationally restricted side chain. It is a potent and reasonably selective agonist for the CB₁ cannabinoid receptor, with a K_i of 1.2nM at CB₁ and 5.3nM at CB₂.