Amthamine

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
Amthamine
Amthamine.svg
Names
IUPAC name
5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine
Other names
5-(2-aminoethyl)-4-methyl-2-thiazolamine
2-amino-5-(2-aminoethyl)-4-methylthiazole
Identifiers
142437-67-0 YesY
ChEMBL ChEMBL293762 YesY
ChemSpider 112538 YesY
4025
Jmol 3D model Interactive image
Interactive image
PubChem 126688
  • InChI=1S/C6H11N3S/c1-4-5(2-3-7)10-6(8)9-4/h2-3,7H2,1H3,(H2,8,9) YesY
    Key: LHVRFUVVRXGZPV-UHFFFAOYSA-N YesY
  • InChI=1/C6H11N3S/c1-4-5(2-3-7)10-6(8)9-4/h2-3,7H2,1H3,(H2,8,9)
    Key: LHVRFUVVRXGZPV-UHFFFAOYAV
  • CC1=C(SC(=N1)N)CCN
  • n1c(c(sc1N)CCN)C
Properties
C6H11N3S
Molar mass 157.236 g/mol
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Amthamine is a histamine agonist selective for the H2 subtype.[1] It has been used in vitro and in vivo to study gastric secretion,[2] as well as other functions of the H2 receptor.[3][4][5]

References

  1. ↑ Eriks JC, van der Goot H, Sterk GJ, Timmerman H. Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles. Journal of Medicinal Chemistry. 1992 Aug 21;35(17):3239-46. PMID 1507209
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Ezeamuzie CI, Philips E. Histamine H(2) receptors mediate the inhibitory effect of histamine on human eosinophil degranulation. British Journal of Pharmacology. 2000 Oct;131(3):482-8. PMID 11015298
  4. ↑ Fernandez N, Monczor F, Baldi A, Davio C, Shayo C. Histamine H2 receptor trafficking: role of arrestin, dynamin, and clathrin in histamine H2 receptor internalization. Molecular Pharmacology. 2008 Oct;74(4):1109-18. PMID 18617631
  5. ↑ Threlfell S, Exley R, Cragg SJ, Greenfield SA. Constitutive histamine H2 receptor activity regulates serotonin release in the substantia nigra. Journal of Neurochemistry. 2008 Nov;107(3):745-55. PMID 18761715


<templatestyles src="Asbox/styles.css"></templatestyles>

Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
Retrieved from "https://infogalactic.com/w/index.php?title=Amthamine&oldid=721139010"