Apolipoprotein C4

Apolipoprotein C-IV
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1BY6, 1I5J, 1O8T, 1SOH
Identifiers
Symbols	APOC4 ; APO-CIV; APOC-IV
External IDs	OMIM: 600745 MGI: 87878 HomoloGene: 1245 GeneCards: APOC4 Gene
Gene ontology Molecular function • lipid transporter activity Cellular component • very-low-density lipoprotein particle • high-density lipoprotein particle Biological process • lipid metabolic process • lipid transport • positive regulation of sequestering of triglyceride • triglyceride homeostasis Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	346	11425
Ensembl	ENSG00000267467	ENSMUSG00000074336
UniProt	P55056	Q61268
RefSeq (mRNA)	NM_001646	NM_007385
RefSeq (protein)	NP_001637	NP_031411
Location (UCSC)	Chr 19: 44.94 – 44.95 Mb	Chr 7: 19.68 – 19.68 Mb
PubMed search	[1]	[2]

Apolipoprotein C-IV, also known as apolipoprotein C4, is a protein that in humans is encoded by the APOC4 gene.

Function

Apolipoprotein (apo)C4 gene is a member of the apolipoprotein C gene family. It is expressed in the liver and has a predicted protein structure characteristic of the other genes in this family. Apo C4 is a 3.3-kb gene consisting of 3 exons and 2 introns; it is located 0.5 kb 5' to the APOC2 gene.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.