Apronal
Systematic (IUPAC) name | |
---|---|
(±)-N-Carbamoyl-2-propan-2-ylpent-4-enamide
|
|
Clinical data | |
Routes of administration |
Oral |
Pharmacokinetic data | |
Excretion | Renal |
Identifiers | |
CAS Number | 528-92-7 |
ATC code | N05CM12 (WHO) |
PubChem | CID: 10715 |
ChemSpider | 10264 |
UNII | V18J24E25E |
KEGG | D03975 |
ChEMBL | CHEMBL509282 |
Chemical data | |
Formula | C9H16N2O2 |
Molecular mass | 184.236 g/mol |
|
|
|
|
(verify) |
Apronal (brand name Sedormid), or apronalide, also known as allylisopropylacetylurea or allylisopropylacetylcarbamide, is a hypnotic/sedative drug of the ureide (acylurea) group synthesized in 1926[1] by Hoffmann-La Roche that is no longer used. Though it is not a barbiturate, apronalide is similar in structure to the barbiturates (being an open-chain carbamide instead of having a heterocyclic ring).[2] In accordance, it is similar in action to the barbiturates, although considerably milder in comparison (formerly used as a daytime sedative at doses of 1 to 2 grams every 3 to 4 hours).[2] Upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use.[3]
See also
References
<templatestyles src="Asbox/styles.css"></templatestyles>
<templatestyles src="Asbox/styles.css"></templatestyles>
- Chemical articles having calculated molecular weight overwritten
- Chemical articles with unknown parameter in Infobox drug
- Infobox drug articles without a structure image
- Chemical pages without DrugBank identifier
- Drugs with no legal status
- Alkenes
- GABAA receptor positive allosteric modulators
- Hypnotics
- Sedatives
- Ureas
- Withdrawn drugs
- Alkene stubs
- Sedative stubs