BPY2

Basic charge, Y-linked, 2
Identifiers
Symbols	BPY2 ; BPY2A; VCY2; VCY2A
External IDs	OMIM: 400013 HomoloGene: 128208 GeneCards: BPY2 Gene
Gene ontology Molecular function • protein binding • HECT domain binding Cellular component • nucleus Biological process • spermatogenesis • single fertilization Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9083	n/a
Ensembl	ENSG00000183753	n/a
UniProt	O14599	n/a
RefSeq (mRNA)	NM_004678	n/a
RefSeq (protein)	NP_004669	n/a
Location (UCSC)	Chr Y: 22.97 – 23.01 Mb	n/a
PubMed search	[1]	n/a

Testis-specific basic protein Y 2 also known as basic charge, Y-linked 2 is a protein that in humans is encoded by the BPY2 gene which resides on the Y chromosome.

Function

This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein interacts with ubiquitin protein ligase E3A and may be involved in male germ cell development and male infertility. Three nearly identical copies of this gene exist on chromosome Y; two copies are part of a palindromic region. This record represents the copy outside of the palidromic region.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.