CAMP test

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This is an example of a positive CAMP test indicated by the formation of an arrowhead where the Strep group B (Streptococcus agalactiae) meets the Staphylococcus aureus (white middle streak).

The CAMP test is a test to identify Group B β-streptococci[1][2] based on their formation of a substance (CAMP factor[3]) that enlarges the area of hemolysis formed by β-hemolysin from Staphylococcus aureus. It is frequently used to identify Listeria spp.

CAMP factor

Although usually used to identify group "B", there is some evidence that the CAMP factor gene is present in several groups of streptococci, including group "A".[4]

A similar factor has been identified in Bartonella henselae.[5]

Uses

It can be used to identify Streptococcus agalactiae. Though not strongly beta-hemolytic on its own,[6] it presents with a wedge-shape in the presence of Staphylococcus aureus.[7]

History

CAMP is an acronym for "Christie–Atkins–Munch-Petersen",[8][9][10] for the three researchers who discovered the phenomenon.[11]

It is often incorrectly reported as the product of four people (counting Munch-Petersen as two people).[12] The true relationship (three people) is the reason for two en dashes and then one hyphen in "Christie–Atkins–Munch-Petersen".

The name has no relationship to cyclic adenosine monophosphate (cAMP).

References

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  9. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  10. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  11. ↑ Christie, R., Atkins, NE and Munch-Petersen, E. (1944). A note on a lytic phenomenon shown by group B streptococci. Aust. J. Exp. Biol. Med. Sci. 22, 197-200
  12. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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