Chlornaltrexamine
From Infogalactic: the planetary knowledge core
Names | |
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IUPAC name
6-(Bis(2-chloroethyl)amino)-17-(cyclopropylmethyl)-4,5-epoxy-(5α,6β)-morphinan-3,14-diol
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Other names
α-Chlornaltrexamine
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Identifiers | |
67025-94-9 | |
ChemSpider | 4588895 |
Jmol 3D model | Interactive image |
PubChem | 5486190 |
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Properties | |
C24H32Cl2N2O3 | |
Molar mass | 467.43 g/mol |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
Chlornaltrexamine is an irreversible mixed agonist–antagonist for μ-opioid receptors, which forms a covalent bond to the active site. It is twenty-two times more potent than morphine. Its alkylating group is a bis(chloroalkyl)amino-residue similar to that of the nitrogen mustards.[1] [2] [3] [4] [5][6]
See also
- Chloroxymorphamine, an irreversible full agonist
- Naloxazone, an irreversible μ-opioid antagonist
- Oxymorphazone, an irreversible full agonist
References
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- Alkylating agents
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