Chrysophanic acid
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| Names | |
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| IUPAC name
1,8-Dihydroxy-3-methyl-9,10-anthraquinone
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| Identifiers | |
| ChEBI | CHEBI:3687 |
| ChemSpider | 9793 |
| Jmol 3D model | Interactive image |
| PubChem | 10208 |
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| Properties | |
| C15H10O4 | |
| Molar mass | 254.24 g·mol−1 |
| Vapor pressure | {{{value}}} |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
Chrysophanic acid, also known as chrysophanol, is a fungal isolate and a natural anthraquinone with anti-cancer activity.[1]
Drug action
Chrysophanol induces the necrosis of cancer cells via a reduction in ATP levels.[2] Chrysophanol attentuates the effects of lead exposure in mice by reducing hippocampal neuronal cytoplasmic edema, enhancing mitochondrial crista fusion, significantly increasing memory and learning abilities, reducing lead content in blood, heart, brain, spleen, kidney and liver, promoting superoxide dismutase and glutathione peroxidase activities and reducing malondialdehyde level in the brain, kidney and liver. [3]
Notes
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- ↑ In lead-exposed neonatal mice, chrysophanol attenuates injury to hippocampal neurons. Zhang et al. (2014) http://www.medicalnewstoday.com/releases/279724.php
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