Delmadinone acetate

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Delmadinone acetate
File:Delmadinone acetate.svg
Systematic (IUPAC) name
6-chloro-3,20-dioxopregna-1,4,6-trien-17-yl acetate
Identifiers
CAS Number 13698-49-2
ATCvet code QG03DX91 (WHO)
PubChem CID: 10135765
ChemSpider 8311278
ChEMBL CHEMBL2104598
Chemical data
Formula C23H27ClO4
Molecular mass 402.911 g/mol
  • O=C\1\C=C/[C@]4(C(=C/1)C(\Cl)=C/[C@@H]2[C@@H]4CC[C@@]3([C@@](OC(=O)C)(C(=O)C)CC[C@@H]23)C)C
  • InChI=1S/C23H27ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h5,8,11-12,16-18H,6-7,9-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1
  • Key:CGBCCZZJVKUAMX-DFXBJWIESA-N

Delmadinone acetate (INN, USAN, BAN) (brand names Delmate, Estrex, Tardak, Tardastren, Tardastrex, Vetadinon, Zenadrex), sometimes abbreviated as DMA, and also known as 1,6-bisdehydro-6-chloro-17α-acetoxyprogesterone, is a steroidal progestin with antigonadotropic (and hence, antiandrogenic and antiestrogenic) properties which is used to treat androgen-associated conditions in veterinary medicine.[1][2][3] It must be used with care as it has the potential to cause adrenal insufficiency via inhibition of adrenocorticotropic hormone (ACTH) secretion from the pituitary gland.[4]

See also

References

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