Extracellular matrix protein 1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Extracellular matrix protein 1 is a protein that in humans is encoded by the ECM1 gene.[1][2][3]
This gene encodes an extracellular protein containing motifs with a cysteine pattern characteristic of the cysteine pattern of the ligand-binding "double-loop" domains of the albumin protein family. This gene maps outside the epidermal differentiation complex (EDC), a cluster of three gene families involved in epidermal differentiation. Alternatively spliced transcript variants encoding distinct isoforms have been described.[3]
Diseases
ECM1 is implicated in breast cancer, thyroid cancer, hepatocellular carcinoma, and other cancers, and also in lipoid proteinosis and ulcerative colitis[4] (see the Atlas of Genetics and Cytogenetics in Oncology and Haematology,[5]).
See also
References
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- ↑ http://atlasgeneticsoncology.org/Genes/ECM1ID40398ch1q21.html
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Further reading
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