Casbene synthase

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casbene synthase
Identifiers
EC number 4.2.3.8
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a casbene synthase (EC 4.2.3.8) is an enzyme that catalyzes the chemical reaction

geranylgeranyl diphosphate \rightleftharpoons casbene + diphosphate

Hence, this enzyme has one substrate, geranylgeranyl diphosphate, and two products, casbene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming). Other names in common use include casbene synthetase, and geranylgeranyl-diphosphate diphosphate-lyase (cyclizing). This enzyme participates in diterpenoid biosynthesis.

References

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