Ephrin B2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Ephrin-B2 is a protein that in humans is encoded by the EFNB2 gene.[1]

Function

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.[2]

Interactions

EFNB2 has been shown to interact with EPHA3.[3][4]

References

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  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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Further reading

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