EIF5A

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene.[1]

It is the only known protein to contain the unusual amino acid hypusine [N (ε)- (4-amino-2-hydroxybutyl)-lysine], which is synthesized on eIF5A at a specific lysine residue from the polyamine spermidine by two catalytic steps.[2]

EF-P is the prokaryotic homolog of eIF5A, which is also modified post-translationally in a similar but distinct way.[3][4]


References

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Further reading

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