Escaline

Escaline
Names
	IUPAC name 2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine
	Other names 3,5-Dimethoxy-4-ethoxy-phenethylamine; 2-(4-Ethoxy-3,5-dimethoxyphenyl)ethanamine
Identifiers
CAS Number	39201-82-6
ChEMBL	ChEMBL319415
ChemSpider	35053
Jmol 3D model	Interactive image; Interactive image
PubChem	38240
	InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3 Key: RHOGRSKNWDNCDN-UHFFFAOYSA-N ; InChI=1/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3 Key: RHOGRSKNWDNCDN-UHFFFAOYAR ;
	SMILES NCCC1=CC(OC)=C(OCC)C(OC)=C1 ; O(c1c(OC)cc(cc1OC)CCN)CC ;
Properties
Chemical formula	C12H19NO3
Molar mass	225.28 g/mol
Melting point	165 to 166 °C (329 to 331 °F; 438 to 439 K) (hydrochloride)
Vapor pressure	{{{value}}}
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

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Escaline or 3,5-methoxy-4-ethoxy phenethylamine is a psychedelic drug and entheogen of the phenethylamine class of compounds. Escaline was first synthesized and reported in the scientific literature by Benington, et al., in 1954, but was later re-examined in the laboratory of David E. Nichols, who prepared a series of mescaline analogues that included escaline, proscaline, and isoproscaline. The effects of this and related mescaline analogues in humans were first described by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as 40 to 60 mg, consumed orally. The duration of action was stated to be 8 – 12 hours.

Escaline is the phenethylamine analog of 3C-E and the 4-ethoxy analog of mescaline.

Legal status

Escaline is illegal in Sweden as of 26. January 2016.^[1]

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