File:Transformer splicing.gif
Summary
Alternative splicing of the Transformer gene transcript in Drosophila melanogaster. In males, the splicing factor U2AF binds to the 3' splice junction of intron 1, allowing the transcript to be spliced at this point. The mRNA then contains the entire exon 2, including an early stop codon. The protein encoded is truncated and non-functional. In females, the master sex determination factor Sex Lethal (Sxl) binds at the 3' splice junction, competing with U2AF. Splicing then occurs at an alternative 3' splice junction within exon 2. The mRNA that results encodes a functional Tra protein.
Licensing
Lua error in package.lua at line 80: module 'strict' not found.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 15:48, 15 January 2017 | | 953 × 488 (16 KB) | 127.0.0.1 (talk) | Alternative splicing of the <i>Transformer</i> gene transcript in <i>Drosophila melanogaster</i>. In males, the splicing factor U2AF binds to the 3' splice junction of intron 1, allowing the transcript to be spliced at this point. The mRNA then contains the entire exon 2, including an early stop codon. The protein encoded is truncated and non-functional. In females, the master sex determination factor Sex Lethal (Sxl) binds at the 3' splice junction, competing with U2AF. Splicing then occurs at an alternative 3' splice junction within exon 2. The mRNA that results encodes a functional Tra protein. |
- You cannot overwrite this file.
File usage
The following page links to this file:
