Gigantocellular reticular nucleus

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Gigantocellular reticular nucleus
Details
Latin nucleus reticularis gigantocellularis
Identifiers
NeuroNames hier-727
NeuroLex ID Nucleus gigantocellularis
Dorlands
/Elsevier
n_11/12581282
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TH {{#property:P1694}}
TE {{#property:P1693}}
FMA {{#property:P1402}}
Anatomical terms of neuroanatomy
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

The gigantocellular nucleus, as the name indicates, is mainly composed of the so-called giant neuronal cells.

This nucleus has been known to innervate the caudal hypoglossal nucleus, and responds to glutamateric stimuli.

The gigantocellular nucleus excites the hypoglossal nucleus, and can play a role in the actions of the said nerve.[1]

This nucleus receives connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus.

Retrograde studies have shown that the deep mesencephalic reticular formation and oral pontine reticular nucleus project to the gigantocellular nucleus.

The dorsal rostral section of the nucleus reticularis gigantocellularis is also involved mediating in expiration (or out-breathing) along with the parvocellular nucleus.

References

  1. Yang, CC et al. Excitatory innervation of caudal hypoglossal nucleus from nucleus reticularis gigantocellularis in the rat. Neuroscience. 1995 Mar;65(2):365-74.

It also receives inputs from the pedunculopontine nucleus.


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