Gossypetin
From Infogalactic: the planetary knowledge core
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| Names | |
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| IUPAC name
2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxychromen-4-one
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| Other names
Articulatidin
Equisporol 3,3',4',5,7,8-Hexahydroxyflavone 3,5,7,8,3',4'-Hexahydroxyflavone |
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| Identifiers | |
489-35-0  |
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| ChEBI | CHEBI:16400  |
| ChEMBL | ChEMBL253570 |
| ChemSpider | 4444247 |
| Jmol 3D model | Interactive image |
| PubChem | 5280647 |
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| Properties | |
| C15H10O8 | |
| Molar mass | 318.23 g/mol |
| Vapor pressure | {{{value}}} |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Gossypetin is a flavonol, a type of flavonoid. It has been isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle) and exhibits a strong antibacterial activity.[1][2]
Gosspetin has been found to act as an antagonist of TrkB.[3]
Metabolism
The enzyme 8-hydroxyquercetin 8-O-methyltransferase uses S-adenosyl methionine and gossypetin to produce S-adenosylhomocysteine and 3,5,7,3',4'-pentahydroxy-8-methoxyflavone. Recently it was shown that gossypetin has radioprotective activity.
See also
References
- ↑ Antibacterial activity of gossypetin isolated from hibiscus sabdariffa
- ↑ Amitava Khan, Krishnendu Manna, Chinchubose, Mahuya Sinha, Dipesh Kr Das, Swaraj Bandhu Kesh, Anindita Chakrabarty, Asoke Banerji & Sanjit Dey: Gossypetin, a naturally occurring hexahydroxy flavones ameliorates gamma radiation mediated DNA damage International Journal Of Radiation Biology (2013):89(11): 965-975.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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