Isopropylphenidate

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Isopropylphenidate
Isopropylphenidate structure.png
Systematic (IUPAC) name
propan-2-yl 2-phenyl-2-(piperidin-2-yl)acetate
Clinical data
Legal status
Identifiers
CAS Number 93148-46-0 N
PubChem CID: 68314762
ChemSpider 48062090
Chemical data
Formula C16H23NO2
Molecular mass 261.37 g·mol−1
  • C1(=CC=CC=C1)C(C(=O)OC(C)C)C2CCCCN2
  • InChI=1S/C16H23NO2/c1-12(2)19-16(18)15(13-8-4-3-5-9-13)14-10-6-7-11-17-14/h3-5,8-9,12,14-15,17H,6-7,10-11H2,1-2H3
  • Key:AZVPADMEIMLODT-UHFFFAOYSA-N

Isopropylphenidate (also known as IPH and IPPD) is a piperidine based stimulant drug, closely related to methylphenidate, but with the methyl ester replaced by an isopropyl ester. It has similar effects to methylphenidate but with a longer duration of action,[1][2] and was banned in the UK as a Temporary Class Drug from April 2015 following its unapproved sale as a designer drug.[3]

See also

References

  1. Markowitz JS, Zhu HJ, Patrick KS. Isopropylphenidate: an ester homolog of methylphenidate with sustained and selective dopaminergic activity and reduced drug interaction liability. Journal of Child and Adolescent Psychopharmacology. 2013 Dec;23(10):648-54. doi: 10.1089/cap.2013.0074. PMID 24261661
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  3. Methylphenidate-based NPS: A review of the evidence of use and harm. Advisory Council on the Misuse of Drugs, 31 March 2015