KRT85

Keratin 85, type II
Identifiers
Symbols	KRT85 ; ECTD4; HB5; Hb-5; K85; KRTHB5; hHb5
External IDs	OMIM: 602767 MGI: 1859268 HomoloGene: 37603 GeneCards: KRT85 Gene
Gene ontology Molecular function • structural molecule activity Cellular component • extracellular space • keratin filament Biological process • epidermis development Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3891	406219
Ensembl	ENSG00000135443	ENSMUSG00000047641
UniProt	P78386	Q6IMF0
RefSeq (mRNA)	NM_001300810	NM_001003668
RefSeq (protein)	NP_001287739	NP_001003668
Location (UCSC)	Chr 12: 52.36 – 52.37 Mb	Chr 15: 101.43 – 101.44 Mb
PubMed search	[1]	[2]

Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.