Lesogaberan

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Lesogaberan
Lesogaberan.svg
Lesogaberan ball-and-stick model.png
Names
IUPAC name
((R)-3-Amino-2-fluoropropyl)phosphinic acid
Other names
AZD-3355
Identifiers
344413-67-8 YesY=  YesY
ChEMBL ChEMBL448343 N
ChemSpider 23254384 N
7705
Jmol 3D model Interactive image
PubChem 9833984
UNII 4D6Q6HGC7Z YesY
  • InChI=1S/C3H9FNO2P/c4-3(1-5)2-8(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m1/s1 N
    Key: LJNUIEQATDYXJH-GSVOUGTGSA-N N
  • InChI=1/C3H9FNO2P/c4-3(1-5)2-8(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m1/s1
    Key: LJNUIEQATDYXJH-GSVOUGTGBQ
  • O=P([H])(C[C@@H](CN)F)O
Properties
C3H9FNO2P
Molar mass 141.08 g·mol−1
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Lesogaberan (AZD-3355) was[1] an experimental drug candidate developed by AstraZeneca for the treatment of gastroesophageal reflux disease (GERD).[2] As a GABAB receptor agonist,[3] it has the same mechanism of action as baclofen, but is anticipated to have fewer of the central nervous system side effects that limit the clinical use of baclofen for the treatment of GERD.[4]

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.

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