Loteprednol
From Infogalactic: the planetary knowledge core
(Redirected from Loteprednol etabonate)
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| Systematic (IUPAC) name | |
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Chloromethyl 17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
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| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a606003 |
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| Legal status |
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| Identifiers | |
| CAS Number | 82034-46-6  |
| ATC code | S01BA14 (WHO) |
| PubChem | CID: 444025 |
| IUPHAR/BPS | 7085 |
| DrugBank | DB00873  |
| ChemSpider | 392049 |
| UNII | Z8CBU6KR16 |
| KEGG | D01689 |
| ChEMBL | CHEMBL1201389 |
| Chemical data | |
| Formula | C24H31ClO7 |
| Molecular mass | 466.951 g/mol |
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Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used in ophthalmology. Marketed by Bausch and Lomb as Lotemax in the U.S., ocular applications for this drug include the treatment of inflammation of the eye due to allergies (according to the prescription information sheet), as well as chronic forms of keratitis (e.g.: adenoviral and Thygeson’s keratitis), vernal keratoconjunctivitis, pingueculitis, and episcleritis. The drug has little or no effect on intraocular pressure.
See also
References
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