MRK-016

MRK-016

Names
IUPAC name 3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)pyrazolo(1,5-d)(1,2,4)triazine
Identifiers
CAS Number	783331-24-8
ChemSpider	5293780
Jmol 3D model	Interactive image
SMILES CN1N=CN=C1COC1=NN2C(C=NN=C2C2=NOC(C)=C2)=C1C(C)(C)C
Properties
Chemical formula	C17H20N8O2
Molar mass	368.40 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

MRK-016 is a selective α₅ subunit-containing GABA_A negative allosteric modulator that has nootropic properties. It has been found to produce rapid, ketamine-like antidepressant effects in animal models of depression.

See also

• L-655,708