Mobetron

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The Mobetron is the only portable, self-shielded electron linear accelerator designed to deliver Intraoperative radiation therapy (IORT) to cancer patients during surgery. The system was invented and commercialized by IntraOp Medical Corporation (IntraOp) in 1997 under the leadership of Donald Goer and other cofounders Russ Schonberg, Mary Louise Meruk, Jerry Vaeth, and Gene Haynes.[1] The Mobetron has made it possible to use LINAC-based radiation for cancer treatment in a standard Operating Room without the need for shielding.

Electron IORT which has been practiced since the late 1960s had historically only been possible using traditional linear accelerators in shielded bunkers. This was a major hindrance to the adoption of IORT as it added significant cost to treatment and logistical complications to surgery. The Mobetron made electron IORT portable by leveraging x-band LINAC technology combined with redundant shielding and an integrated beam stopper. This results in a highly safe radiation device with very low stray radiation[2] contained in a small foot print.

The Mobetron has treated over 15,000 patients in fourteen different countries around the world.

Technical Features

  • Energies: 6,9,12 MeV
  • Depth: 1-4 cm D80
  • Stray Radiation: less than 6µSv @ 3 meters
  • Motion Control:
    • Rotation: +/- 45 degrees
    • Tilt +10 degrees / - 30 degrees
    • Lateral/Longitudinal: +/- 5cm
    • Vertical: 30cm
  • Soft docking laser alignment system
  • QA System: AAPM TG72 Compliant

Clinical Uses

The Mobetron and Electron IORT have been used to treat over 20 different types of cancer. The most common cancers treated by the Mobetron are breast cancer, pancreatic cancer, colorectal cancer, sarcomas, head and neck cancers, and GYN cancers.

Treatment Locations

North America

United States

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  • Mayo Clinic, Scottsdale, AZ
  • University of California at San Francisco, CA
  • Stanford Hospital and Clinics, Palo Alto, CA[3]
  • St. Joseph Hospital, Orange, CA[4]
  • Scripps Health, LaJolla, CA
  • University of Louisville, KY
  • Christ Advocate Hospital, Evergreen Park, IL
  • St. Vincent's Hospital, Indianapolis, IN
  • St. Luke’s Iowa Health Center, Cedar Rapids
  • Massachusetts General Hospital, Cambridge, MA
  • University of North Carolina, Chapel Hill, NC
  • The Ohio State University, Columbus, OH[5]
  • University Hospital of Cleveland, Case Western, OH
  • Oregon Health and Science University, Portland, OR
  • Avera McKennan Hospital, Sioux Falls, SD
  • University of Washington, Seattle, WA

Europe

Austria

  • Barmherzige Schwestern Hospital, Linz

Belgium

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  • St. Augustinus Hospital, Antwerp
  • Jules Bordet Institute
  • Centre Hospitalier Universitaire de Tivoli

Germany

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  • CDT Strahleninstitut, Koln
  • University Hospital Giessen and Marburg GmbH – Marburg
  • Marien Hospital Dusseldorf GmBH
  • Helios Berlin Buch, Berlin
  • University of Heidelberg, Heidelberg
  • Universitäts Klinikum Freiburg, Freiburg

Italy

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  • Ospedale Borgo Trento, Verona
  • Azienda Ospedaliera S. Croce e Carle, Cuneo
  • Centro di Riferimento Oncologico, Aviano
  • Ospedale Maggiore della Carita, U. of Novara, Novara
  • Ospedali Riuniti, Trieste

Netherlands

  • MCH Westeinde, Den Haag

Poland

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  • Jagiellonian University, Krakow,
  • Wielkopolskie Centrum Onkologii Cancer Center, Poznan
  • Centrum Onkologii, Bydgoszcz

Turkey

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  • Ministry of Health - Istanbul
  • Ministry of Health - Ankara

Asia

China

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  • Beijing Tumor Hospital (医学科学院肿瘤医院,mobetron 1000)
  • Beijing General Hospital (PLA 301)(解放军总医院,mobetron 1000)
  • Shanghai Tumor Hospital (上海肿瘤医院,mobetron 1000)
  • Shanghai Ruijin Hospital (上海瑞金医院,mobetron 1000)
  • Peking Union Hospital (CAMS) – Beijing (北京协和医院,mobetron 1000)
  • XuanWu Hospital - Beijing (宣武医院,mobetron 1000)
  • PLA 307 – Beijing (解放军第307医院,mobetron 1000)
  • China Medical University, Shenyang City (医科大学附属第一医院, mobetron 2000)

Japan

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  • Nagoya University Hospital
  • Gunma Prefectural Hospital

Thailand

  • Siriraj Hospital, Mahidol University, Bangkok

See also

References

  1. M.L. Meurk. The Mobetron: A New Concept for IORT, 1997
  2. Krechetov. Shielding assessment of a mobile electron accelerator for intra-operative radiotherapy, 2010,
  3. Stanford Selects IntraOp Mobetron, 2006
  4. Saint Joseph Health IORT
  5. Ohio State University Acquires Mobetron, 2004

External links