CHRNA9
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Neuronal acetylcholine receptor subunit alpha-9 is a protein that in humans is encoded by the CHRNA9 gene.[1]
This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.[1]
Selective block of α9α10 nicotinic acetylcholine receptors by the conotoxin RgIA has been shown to be analgesic in an animal model of nerve injury pain.[2]
See also
References
Further reading
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External links
- CHRNA9 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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