Neutrophil cytosolic factor 1
From Infogalactic: the planetary knowledge core
(Redirected from NCF1)
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene.[1]
Function
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.[1] p47 is vital to the activation of NADPH oxidase. P47 becomes heavily phosphorylated
Interactions
Neutrophil cytosolic factor 1 has been shown to interact with:
References
- ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
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Further reading
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