NEFA (drug)

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NEFA
NEFA.svg
Systematic (IUPAC) name
(4aR,9aS)-N-Ethyl-4,4a,9,9a-tetrahydro-1H-fluoren-4a-amine
Chemical data
Formula C15H19N
Molecular mass 213.3181 g/mol
  • CCNC12C(CC=CC2)CC3=CC=CC=C31
  (verify)

NEFA is a moderate affinity NMDA antagonist (IC50 = 0.51 μM). It is a structural analog of phencyclidine.[1] It was first synthesized by a team at Parke Davis in the late 1950s.[2]

References

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  2. GB Patent 893920 - Polycyclic amino compounds and methods for their production


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