NMP-7

NMP-7

Systematic (IUPAC) name
(9-pentylcarbazol-3-yl)-piperidin-1-ylmethanone
Identifiers
CAS Number	1358039-07-2
PubChem	CID: 46871949
ChemSpider	27470961
Chemical data
Formula	C23H28N2O
Molecular mass	348.480 g/mol
SMILES c3cccc1c3n(CCCCC)c(cc2)c1cc2C(=O)N4CCCCC4
InChI InChI=1S/C23H28N2O/c1-2-3-7-16-25-21-11-6-5-10-19(21)20-17-18(12-13-22(20)25)23(26)24-14-8-4-9-15-24/h5-6,10-13,17H,2-4,7-9,14-16H2,1H3 Key:NZEVKZAEMSMLMC-UHFFFAOYSA-N

NMP-7 is a drug which acts as both a non-selective agonist of the CB₁ and CB₂ cannabinoid receptors, and also as a blocker of T-type calcium channels, the target of anticonvulsant drugs such as ethosuximide. NMP-7 has an agonist EC₅₀ of 96.9nM at CB₁ and 10.5nM at CB₂, and an IC₅₀ of 1.84μM for blocking Cav3.2 T-type calcium channels. In animal studies it produces potent analgesic effects in a variety of different tests.