Nitroxazepine

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Nitroxazepine
Nitroxazepine.png
Systematic (IUPAC) name
10-[3-(dimethylamino)propyl]-2-nitrodibenzo[b,f][1,4]oxazepin-11(10H)-one
Clinical data
Legal status
  • ℞ (Prescription only)
Routes of
administration
Oral
Identifiers
CAS Number 16398-39-3
ATC code none
PubChem CID: 27857
ChemSpider 25919
Chemical data
Formula C18H19N3O4
Molecular mass 341.36 g/mol
  • [O-][N+](=O)c2ccc1Oc3c(N(C(=O)c1c2)CCCN(C)C)cccc3

Nitroxazepine (trade name Sintamil) is a tricyclic antidepressant (TCA) which was introduced by Ciba-Geigy (now Novartis) for the treatment of depression in India in 1982.[1] It is also indicated for the treatment of nocturnal enuresis.[1] Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor and has similar effects to imipramine, but with certain advantages, such as lower anticholinergic side effects.[2][3][4]

See also

References

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