Oroxylin A
From Infogalactic: the planetary knowledge core
Skeletal formula | |
Ball-and-stick model of oroxylin A | |
Names | |
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IUPAC name
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one
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Other names
Baicalein 6-methyl ether
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Identifiers | |
480-11-5 | |
ChEBI | CHEBI:61668 |
ChemSpider | 4478428 |
Jmol 3D model | Interactive image |
PubChem | 5320315 |
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Properties | |
C16H12O5 | |
Molar mass | 284.26 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
Oroxylin A is an O-methylated flavone, a chemical compound that can be found in the medicinal plant Scutellaria baicalensis[1] and the Oroxylum indicum tree.[2] It has demonstrated activity as a dopamine reuptake inhibitor,[3] and is also a negative allosteric modulator of the benzodiazepine site of the GABAA receptor.[3][4][5] Oroxylin A has been found to improve memory consolidation in mice by elevating brain-derived neurotrophic factor (BDNF) levels in the hippocampus.[6]
See also
References
- ↑ Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography. Hua-Bin Li and Feng Chen, Journal of Chromatography A, 13 May 2005, Volume 1074, Issues 1–2, pages 107–110, doi:10.1016/j.chroma.2005.03.088
- ↑ The constitution of oroxylin-A, a yellow colouring matter from the root-bark of Oroxylum indicum, vent R. C. Shah, C. R. Mehta and T. S. Wheeler
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Categories:
- Pages with broken file links
- Articles without KEGG source
- Articles without UNII source
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- Chemical articles using a fixed chemical formula
- O-Methylated flavones
- Resorcinols
- Dopamine reuptake inhibitors
- GABAA receptor negative allosteric modulators
- Nootropics
- Aromatic compound stubs