Oxyphil cell (parathyroid)
Oxyphil cell | |
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High magnification micrograph of parathyroid. H&E stain. The cells with orange/pink staining cytoplasm are oxyphil cells
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Identifiers | |
MeSH | Oxyphil+Cells |
Code | TH H3.08.02.5.00005 |
TA | Lua error in Module:Wikidata at line 744: attempt to index field 'wikibase' (a nil value). |
TH | {{#property:P1694}} |
TE | {{#property:P1693}} |
FMA | {{#property:P1402}} |
Anatomical terminology
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]
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In the parathyroid gland, the parathyroid oxyphil cell is larger and darker than the parathyroid chief cell.[1]
These cells can be found in clusters in the center of the section and at the periphery.[2][3][4][5] Oxyphil cells appear at the onset of puberty, but have no known function. With nuclear medicine scans, they selectively take up the Technetium-sestamibi complex radiotracer dye to allow delineation of glandular anatomy.[6] Oxyphil cells have been shown to express parathyroid-relevant genes found in the chief cells and have the potential to produce additional autocrine/paracrine factors, such as Parathyroid hormone-related protein (PTHrP) and calcitriol.[7] More work needs to be done to fully understand the functions of these cells and their secretions.
References
- ↑ Histology image:15002loa from Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Gartner, p. 208, Fig. 3
- ↑ Ross, p. 628, Fig. 1
- ↑ DiFiore, pp. 270 - 271
- ↑ Wheater, pp. 312 - 313
- ↑ "Minimally Invasive Radio-guided Surgery for Primary Hyperparathyroidism," Annals of Surgical Oncology 12/07 14(12) pp 3401-3402
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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