Oxyphil cell (parathyroid)

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Oxyphil cell
Parathyroid gland high mag-cropped2.jpg
High magnification micrograph of parathyroid. H&E stain. The cells with orange/pink staining cytoplasm are oxyphil cells
Identifiers
MeSH Oxyphil+Cells
Code TH H3.08.02.5.00005
TA Lua error in Module:Wikidata at line 744: attempt to index field 'wikibase' (a nil value).
TH {{#property:P1694}}
TE {{#property:P1693}}
FMA {{#property:P1402}}
Anatomical terminology
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

In the parathyroid gland, the parathyroid oxyphil cell is larger and darker than the parathyroid chief cell.[1]

These cells can be found in clusters in the center of the section and at the periphery.[2][3][4][5] Oxyphil cells appear at the onset of puberty, but have no known function. With nuclear medicine scans, they selectively take up the Technetium-sestamibi complex radiotracer dye to allow delineation of glandular anatomy.[6] Oxyphil cells have been shown to express parathyroid-relevant genes found in the chief cells and have the potential to produce additional autocrine/paracrine factors, such as Parathyroid hormone-related protein (PTHrP) and calcitriol.[7] More work needs to be done to fully understand the functions of these cells and their secretions.

References

  1. Histology image:15002loa from Lua error in package.lua at line 80: module 'strict' not found.
  2. Gartner, p. 208, Fig. 3
  3. Ross, p. 628, Fig. 1
  4. DiFiore, pp. 270 - 271
  5. Wheater, pp. 312 - 313
  6. "Minimally Invasive Radio-guided Surgery for Primary Hyperparathyroidism," Annals of Surgical Oncology 12/07 14(12) pp 3401-3402
  7. Lua error in package.lua at line 80: module 'strict' not found.

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