Pasteurellaceae
| Pasteurellaceae | |
|---|---|
 |
|
| Haemophilus ducreyi | |
| Scientific classification | |
| Kingdom: | |
| Phylum: | |
| Class: | |
| Order: |
Pasteurellales
|
| Family: |
Pasteurellaceae
Castellani & Chalmers, 1919
|
| Genera | |
|
Actinobacillus |
|
Lua error in Module:Taxonbar/candidate at line 22: attempt to index field 'wikibase' (a nil value).
The Pasteurellaceae comprise a large family of Gram-negative bacteria. Most members live as commensals on mucosal surfaces of birds and mammals, especially in the upper respiratory tract.[1] Pasteurellaceae are typically rod-shaped, and are a notable group of facultative anaerobes. They can be distinguished from the related Enterobacteriaceae by the presence of oxidase, and from most other similar bacteria by the absence of flagella.
Bacteria in the family Pasteurellaceae have been classified into a number of genera based on metabolic properties, but these classifications are not generally accurate reflections of the evolutionary relationships between different species. H. influenzae was the first organism to have its genome sequenced and has been studied intensively by genetic and molecular methodologies.
Molecular signatures
Comparative analyses of Pasteurellaceae genomes have identified large numbers (>20) of conserved signature indels (CSIs) in different important proteins that are uniquely shared by all sequenced Pasteurellaceae species/strains, but are not found in any other bacteria. Based upon many other CSIs that are specific for subgroups of Pasteurellaceae species, it has been proposed to divide the family into at least two clades .[2] One proposed clade includes Aggregatibacter, Pasteurella, Actinobacillus succinogenes, Haemophilus influenzae, Haemophilus somnus, and Mannheimia succiniciproducens, while the other includes Actinobacillus minor, Actinobacillus pleuropneumoniae, Haemophilus ducryi, Haemophilus parasuis, and Mannheimia haemolytica.
DNA sequence
DNA sequence data are available for these Pasteurellaceae: Aggregatibacter actinomycetemcomitans strain HK1651, Actinobacillus pleuropneumoniae strains L20 and sv1 4074, Haemophilus ducreyi strain 35000HP, Haemophilus influenzae strains 86-028NP, R2846, R2866, and Rd, Histophilus somni strains 129Pt and 2336, Mannheimia haemolytica A1 strain ATCC BAA-410, Mannheimia succiniciproducens strain MBEL55E, and Pasteurella multocida strain Pm70.[3]
