Pheneturide

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Pheneturide
Pheneturide.svg
Systematic (IUPAC) name
(RS)-N-carbamoyl-2-phenyl-butanamide
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 90-49-3 N
ATC code N03AX13 (WHO)
PubChem CID: 72060
ChemSpider 65046 YesY
UNII 878CEJ4HGX YesY
KEGG D01190 YesY
Chemical data
Formula C11H14N2O2
Molecular mass 206.241 g/mol
  • O=C(N)NC(=O)C(c1ccccc1)CC
  • InChI=1S/C11H14N2O2/c1-2-9(10(14)13-11(12)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H3,12,13,14,15) YesY
  • Key:AJOQSQHYDOFIOX-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride),[1] also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class.[2][3] It is considered to be obsolete,[4] and is now seldom used.[5] It is marketed in Europe, including in Poland, Spain, and the United Kingdom.[6] Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide,[7] but is less toxic in comparison, despite still being a toxic drug.[8] As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed.[8] Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.[5][6]

See also

References

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