Pipofezine

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Pipofezine
Pipofezine.png
Systematic (IUPAC) name
5-methyl-3-(4-methylpiperazin-1-yl)pyridazino[3,4-b][1,4]benzoxazine
Clinical data
Legal status
  • ℞ (Prescription only)
Routes of
administration		 Oral
Identifiers
CAS Number 24886-52-0
ATC code none
PubChem CID: 159977
ChemSpider 140640
UNII P8T739L1FA YesY
Chemical data
Formula C16H19N5O
Molecular mass 297.36 g/mol

Pipofezine (Azafen or Azaphen) is a tricyclic antidepressant (TCA) approved in Russia for the treatment of depression.[1][2][3][4] It was introduced in the late 1960s and is still used today.[5][6]

Pipofezine has been shown to act as a potent inhibitor of the reuptake of serotonin.[7][8] In addition to its antidepressant action, pipofezine has sedative effects as well, suggesting antihistamine activity.[4] Other properties such as anticholinergic or antiadrenergic actions are less clear but are likely.[citation needed]

References

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