Potassium canrenoate
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File:Canrenoate potassium.png | |
Systematic (IUPAC) name | |
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potassium 3-[(8R,9S,10R,13S,14S,17R)-
17-hydroxy-10,13-dimethyl-3-oxo-2,8,9, 11,12,14,15,16-octahydro-1H-cyclopenta[a] phenanthren-17-yl]propanoate |
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Clinical data | |
AHFS/Drugs.com | International Drug Names |
Routes of administration |
Intravenous |
Pharmacokinetic data | |
Metabolism | Hepatic |
Excretion | Renal and fecal |
Identifiers | |
CAS Number | 2181-04-6 N |
ATC code | C03DA02 (WHO) |
PubChem | CID: 656614 |
DrugBank | DB09015 N |
ChemSpider | 570975 Y |
UNII | M671F9NLEA N |
ChEMBL | CHEMBL1371200 N |
Synonyms | SC-14266 |
Chemical data | |
Formula | C22H29KO4 |
Molecular mass | 396.5616 g/mol |
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NY (what is this?) (verify) |
Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium,[1] the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group.[2] Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body. Potassium canrenoate is not licensed in the UK, but may sometimes be prescribed off-licence to treat oedema. It is given intravenously.
See also
References
Sulfonamides (and etacrynic acid) |
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Potassium-sparing (at CD) |
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Mineralocorticoids | |
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Antimineralocorticoids |
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Synthesis modifiers | |
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Receptor (ligands) |
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Enzyme |
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Others |
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Enzyme |
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Others |
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Receptor (ligands) |
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Enzyme |
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Others |
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20,22-Desmolase | |
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17α-Hydroxylase, 17,20-Lyase |
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3α-HSD | |
3β-HSD | |
11β-HSD | |
21-Hydroxylase | |
11β-Hydroxylase |
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18-Hydroxylase |
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17β-HSD |
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5α-Reductase |
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Aromatase |
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27-Hydroxylase | |
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