Prednicarbate

Prednicarbate

Systematic (IUPAC) name
(11β)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propionate
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a604021
Routes of administration	Topical
Identifiers
CAS Number	73771-04-7 Y
ATC code	D07AC18 (WHO)
PubChem	CID: 6714002
IUPHAR/BPS	7605
DrugBank	DB01130 N
ChemSpider	5145991 N
UNII	V901LV1K7D N
ChEMBL	CHEMBL1200386 N
Synonyms	[2-[(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
Chemical data
Formula	C27H36O8
Molecular mass	488.57 g/mol
SMILES O=C(OCC(=O)[C@@]1(OC(=O)OCC)CC[C@H]2[C@H]4[C@H]([C@@H](O)C[C@]12C)[C@]/3(/C=C\C(=O)\C=C\3CC4)C)CC
InChI InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1 N Key:FNPXMHRZILFCKX-KAJVQRHHSA-N N
NY (what is this?)  (verify)

Prednicarbate is a relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly. Corticosteroids have always been an important part of the pharmacological arsenal of dermatology; however, their tendency to produce side-effects has caused the need to search for new preparations.

It is nonhalogenated.