RS-56812

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RS-56812
RS-56812 structure.png
Systematic (IUPAC) name
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide
Identifiers
CAS Number 143137-35-3
PubChem CID: 6604789
Chemical data
Formula C18H21N3O2
Molecular mass 311.377 g/mol
  • c14ccccc4n(C)cc1C(=O)C(=O)NC2CN3CCC2CC3
  (verify)

RS-56812 is a potent and selective partial agonist at the 5HT3 receptor.[1] It has been shown to improve performance on animal tests of memory.[2]

References

  1. ↑ Van Hooft JA, Vijverberg HP. RS-056812-198: partial agonist on native and antagonist on cloned 5-HT3 receptors. European Journal of Pharmacology. 1997 Mar 19;322(2-3):229-33. PMID 9098692
  2. ↑ Terry AV Jr, Buccafusco JJ, Prendergast MA, Jackson WJ, Fontana DL, Wong EH, Whiting RL, Eglen RM. The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys. Neuroreport. 1996 Dec 20;8(1):49-54. PMID 9051751


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