Stephen O'Rahilly

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Sir Stephen O'Rahilly
File:Professor Steve O'Rahilly FMedSci (8550871399).jpg
Born Stephen Patrick O'Rahilly
(1958-04-01) 1 April 1958 (age 66)[1]
Citizenship Ireland, United Kingdom
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Alma mater University College Dublin
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Website
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Sir Stephen Patrick O'Rahilly FRS FRCP FRCP FRCPath FRS FMedSci is an Irish-British physician and Professor known for his research into the molecular pathogenesis of human obesity, insulin resistance and related metabolic and endocrine disorders.[2][3][4][5][6][7][8][9][10]

Education

O'Rahilly was raised in Dublin, Ireland[11] and educated at Beneavin College.[1] He attended University College Dublin to study medicine[11]

Research

O'Rahilly has undertaken research at the University of Oxford and Harvard Medical School into diabetes and insulin resistance, before joining the University of Cambridge where he is a Professor of Clinical Biochemistry and Medicine, Director of the University of Cambridge Metabolic Research Laboratories,[12] Director of the MRC Metabolic Diseases Unit,[12] co-director of the Wellcome Trust-MRC Institute of Metabolic Science, Scientific Director of the NIHR Cambridge Biomedical Research Centre, Associate Faculty at the Wellcome Trust Sanger Institute and honorary consultant physician at Addenbrooke's Hospital, Cambridge.[13][14][15]

Awards and honours

O'Rahilly was elected to the Academy of Medical Sciences in 1999, the Royal Society in 2003. His nomination reads: <templatestyles src="Template:Blockquote/styles.css" />

Stephen O'Rahilly has made major contributions to the understanding of the molecular mechanisms underlying human disorders of energy balance and metabolism. His work first established that mutations in single genes could result in severe human obesity and that these defects largely acted through disruption of central satiety mechanisms. These findings have altered clinical approaches to the evaluation of the obese child and have identified a subtype of obesity amenable to dramatically effective therapy. His studies of patients with extreme insensitivity to insulin have also provided new insights into human insulin action and its disruption in states of insulin resistance.[16]

Rahilly became a Foreign Associate of the National Academy of Sciences, in the US in 2011. He was awarded the Heinrich Wieland Prize[17] in 2002, the InBev-Baillet Latour Health Prize in 2010[18] and the Debrecen Award for Molecular Medicine in 2014.[19]

He was knighted in the 2013 Birthday Honours for services to medical research.[20][21]

References

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  5. Stephen O'Rahilly's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
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  11. 11.0 11.1 Ellen Ruppel Shell, Fat Genes, Discover Magazine, May 1, 2000
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  14. Lua error in package.lua at line 80: module 'strict' not found.open access publication - free to read
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  17. Heinrich Wieland Prize Archived November 12, 2013 at the Wayback Machine
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  20. The London Gazette: (Supplement) no. 60534. p. 1. 2013-06-15.
  21. Stephen O'Rahilly knighted, BBC News, 14 June, 3013