Sulfalene

Systematic (IUPAC) name
	4-Amino-N-(3-methoxypyrazinyl)benzenesulfonamide
Clinical data
Trade names	Eadazine, Kelfizina, Kelfizine W, Longum
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
Pharmacokinetic data
Protein binding	60 to 80%
Biological half-life	60 to 65 hours
Excretion	Urinary
Identifiers
CAS Number	152-47-6
ATC code	J01ED02 (WHO) QJ01EQ19 (WHO)
PubChem	CID: 9047
DrugBank	DB00664
ChemSpider	8695
UNII	T6BL4ZC15G
KEGG	D01216
Synonyms	Sulfametopyrazine
Chemical data
Formula	C11H12N4O3S
Molecular mass	280.304 g/mol
	SMILES O=S(=O)(Nc1nccnc1OC)c2ccc(N)cc2 ;
	InChI InChI=1S/C11H12N4O3S/c1-18-11-10(13-6-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15) ; Key:KXRZBTAEDBELFD-UHFFFAOYSA-N ;
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Sulfalene (INN, USAN) or sulfametopyrazine (BAN) is a long-acting sulfonamide antibacterial used for the treatment of chronic bronchitis, urinary tract infections and malaria.^[2]^[3] As of 2014 there were only two countries in which it is currently still marketed: Thailand and Ireland.^[3]

It was discovered by researchers at Farmitalia and first published in 1960 and was marketed as Kelfizina.^[4]^[5]

References

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↑ DrugBank DB00664
↑ ^3.0 ^3.1 Lua error in package.lua at line 80: module 'strict' not found.
↑ Baruffa G. Clinical trials in Plasmodium falciparum malaria with a long-acting sulphonamide. Trans R Soc Trop Med Hyg. 1966;60(2):222-4. PMID 5332105
↑ Per prior citation, the first publication: Camerino B, Palamidessi G (1960) Derivati della parazina II. Sulfonamdopir (in Italian). Gazz Chim Ital 90:1802–1815

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