Sulfur dioxygenase

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Sulfur dioxygenase
Identifiers
EC number 1.13.11.18
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Sulfur dioxygenase (EC 1.13.11.18, sulfur oxygenase, sulfur:oxygen oxidoreductase) is an enzyme with systematic name S-sulfanylglutathione:oxygen oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

sulfur + O2 + H2O \rightleftharpoons sulfite + 2 H+ (overall reaction)
(1a) glutathione + sulfur \rightleftharpoons S-sulfanylglutathione (spontaneous reaction)
(1b) S-sulfanylglutathione + O2 + H2O \rightleftharpoons glutathione + sulfite + 2 H+

This enzyme contains iron.

In humans, sulfur dioxygenase is needed to detoxify sulfide.[3]

References

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External links