Tampramine

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Tampramine
Tampramine.svg
Systematic (IUPAC) name
N,N-dimethyl-3-(6-phenylpyrido[2,3-b][1,4]benzodiazepin-11-yl)propan-1-amine
Clinical data
Legal status
  • Uncontrolled
Routes of
administration		 Oral
Identifiers
CAS Number 83166-18-1
PubChem CID: 6450479
ChemSpider 4953084
UNII 47GSE5RM8N YesY
Chemical data
Formula C27H28N4O4
Molecular mass 472.54 g/mol
  • O=C(O)\C=C\C(=O)O.N\3=C(/c1ccccc1)c2ccccc2N(c4ncccc/34)CCCN(C)C

Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed.[1][2] Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors.[1] It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans.[2]

See also

References

  1. ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
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