Thonzylamine

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Thonzylamine
Thonzylamine.svg
Systematic (IUPAC) name
N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyrimidin-2-ylethane-1,2-diamine
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 91-85-0 N Template:CAS
ATC code D04AA01 (WHO) R01AC06 R06AC06
PubChem CID: 5457
ChemSpider 5258 YesY
UNII R79646H5Z8 YesY
KEGG D08587 YesY
ChEMBL CHEMBL1623738 N
Synonyms Neohetramine
Chemical data
Formula C16H22N4O
Molecular mass 286.372 g/mol
  • n1cccnc1N(CCN(C)C)Cc2ccc(OC)cc2
  • InChI=1S/C16H22N4O/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14/h4-10H,11-13H2,1-3H3 YesY
  • Key:GULNIHOSWFYMRN-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Thonzylamine (or neohetramine)[1] is an antihistamine and anticholinergic used as an antipruritic.

Synthesis

Thonzylamine synthesis: H. L. Friedman and A, V. Tolstouhov, U.S. Patent 2,465,865 (1949).

See also

References

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