Toxiferine

Toxiferine

Identifiers
CAS Number	302-30-7
PubChem	CID: 5281411
ChemSpider	4444760
UNII	9M7D9K3OJI
ChEMBL	CHEMBL231047
Chemical data
Formula	C40H46N4O2
Molecular mass	614.82 g/mol
SMILES [H][C@@]12[C@@]3(CC[N+]2(C)C/C4=C/CO)[C@@]5([H])N(C6=C3C=CC=C6)/C=C7[C@]([C@@]8(CC[N+]9(C)C/%10)[C@]9([H])C[C@]\7([H])C%10=C/CO)([H])N(C%11=C8C=CC=C%11)/C=C5/[C@]4([H])C1

Toxiferine (C-toxiferine I) is a curare toxin. It is a bisindole alkaloid derived from Strychnos toxifera and a nicotinic acetylcholine receptor antagonist.

It is a muscle relaxant that causes paralysis of skeletal muscle, which takes approximately 2 hours to recovery for a moderate dose, and 8 hours of total paralysis with a 20-fold paralytic dose.