Travoprost

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
Travoprost
File:Travoprost structure.svg
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)
phenoxy]-but-1-enyl]-cyclopentyl]hept-5-enoate
Clinical data
Trade names Travatan, Travoprostin is the brand name which is available in preservative free form in India by Eyekare Kilitch Ltd.
AHFS/Drugs.com monograph
MedlinePlus a602027
Pregnancy
category
  • C US
Legal status
  • Rx only (US)
Routes of
administration
Topical (eye drops)
Identifiers
CAS Number 157283-68-6 YesY
ATC code S01EE04 (WHO)
PubChem CID: 5282226
IUPHAR/BPS 7102
DrugBank DB00287 YesY
ChemSpider 4445407 YesY
UNII WJ68R08KX9 YesY
KEGG D01964 YesY
ChEBI CHEBI:746859 YesY
ChEMBL CHEMBL1200799 N
Chemical data
Formula C26H35F3O6
Molecular mass 500.548 g/mol
  • FC(F)(F)c2cc(OC[C@H](O)/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C\C=C/CCCC(=O)OC(C)C)ccc2
  • InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1 YesY
  • Key:MKPLKVHSHYCHOC-AHTXBMBWSA-N YesY
 NYesY (what is this?)  (verify)
File:Travatan.jpg
One 2.5 ml dropperette of Alcon Travatan

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F)[1][2] that works by increasing the outflow of aqueous fluid from the eyes.[3] It is also known by the brand names of Travatan and Travatan Z, manufactured by Alcon, and Travo-Z, manufactured by Micro Labs.

Side effects

Possible side effects of this medication are:

  • May cause blurred vision
  • May cause eyelid redness
  • May permanently darken eyelashes
  • May cause eye discomfort
  • May eventually cause permanent darkening of the iris to brown (heterochromia)
  • May cause a temporary burning sensation during use
  • May cause thickening of the eyelashes
  • May cause inflammation of the prostate gland, restricting urine flow (BPH)

See also

References

  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. Lua error in package.lua at line 80: module 'strict' not found.
  3. Lua error in package.lua at line 80: module 'strict' not found.