URB754
From Infogalactic: the planetary knowledge core
Names | |
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IUPAC name
6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one
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Identifiers | |
86672-58-4 | |
Jmol 3D model | Interactive image |
PubChem | 848487 |
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Properties | |
C16H14N2O2 | |
Molar mass | 266.30 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
URB754 was originally reported by Piomelli et al. to be a potent, noncompetitive inhibitor of monoacylglycerol lipase (MGL).[1] However, recent studies have shown that URB754 failed to inhibit recombinant MGL, and brain FAAH activity was also resistant to URB754.[2] In a later study by Piomelli et al., the MGL-inhibitory activity attributed to URB754 is in fact due to a chemical impurity present in the commercial sample, identified as bis(methylthio)mercurane.[3]
References
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