WAY-208,466

WAY-208,466

Systematic (IUPAC) name
N'-[(2Z)-4-(2,4-dichlorophenyl)-3-(2-methylpropyl)-1,3-thiazol-2(3H)-ylidene]-2-(pyrazin-2-yloxy)acetohydrazide
Identifiers
CAS Number	?
ATC code	none
PubChem	CID: 11820788
ChemSpider	9995440
ChEMBL	CHEMBL571858
Chemical data
Formula	C19H19Cl2N5O2S
Molecular mass	452.36 g/mol
SMILES O=C(N\N=C1/S\C=C(/N1CC(C)C)c2ccc(Cl)cc2Cl)COc3nccnc3

WAY-208,466 is a potent and highly selective full agonist of the 5-HT₆ receptor. It increases GABA levels in the cerebral cortex and tolerance does not appear to occur to this action upon chronic administration. Animal studies have shown that WAY-208,466 produces antidepressant and anxiolytic effects in rodents and it may also be useful in the treatment of obsessive-compulsive disorder.

See also

• WAY-181,187